In a companion review1 we discussed the data supporting the conclusion that at least two subtypes of spectrin exist in mammalian brain. One form is found in the cell bodies, dendrites, and post‐synaptic terminals of neurons (brain spectrin(240/235E)) and the other subtype is located in the axons and presynaptic terminals (brain spectrin(240/235)). Our recent understanding of brain spectrin subtype localization suggests a possible explanation for a conundrum concerning brain 4.1 localization. Amelin, an immunoreactive analogue of red blood cell (rbc) cytoskeletal (...) protein 4.1, is localized in neuronal cell bodies and dendrites when brain sections are stained with antibody against rbc protein 4.1. However, it has recently been suggested that synapsin I, a neuron‐specific phosphoprotein associated with the cytoplasmic surface of small synaptic vesicles, is related to erythrocyte 4.1. In this review we hypothesize that there are at least two forms of brain 4.1: a cell body/dendritic form (amelin) which is detected with rbc protein 4.1 antibody, and a unique form found exclusively in the presynaptic terminal (synapsin I). The binding of synapsin I to brain spectrin(240/235), and its ability to stimulate the spectrin/F‐actin interaction in a phosphorylation‐dependent manner suggests a model for the regulation of synaptic transmission mediated by the neuronal cytoskeleton. (shrink)

Thinking about ethics -- Philosophical ethics -- Why not do wrong? -- Is the ethical a human construct or a factual realm? -- Do you just do what is right or do you try to predict the outcomes? -- Natural law and virtue ethics -- Ethics and the bible -- Learning from the wisdom of the world -- Humanism : do we need god to realize that people just matter? -- Ethical dilemmas -- Dilemmas in bed -- Dilemmas in business (...) -- Dilemmas in medicine -- Dilemmas involving violence and power -- Dilemmas in government and leadership -- Dilemmas and the future : the environment, animals, and plants -- Dilemmas in the cyber world -- Making a decision -- Becoming a morally serious person -- Taking an ethical position. (shrink)

I propose to explain Kant’s novel claim, in the Critique of Pure Reason, that all judgments have a formal modality. I begin by distinguishing the modality of a judgment’s form from the modality of its content, and I suggest that the former is peculiar in merely affecting the subject’s understanding of his own act of judging. I then contrast the modal account of such an understanding (in terms of the possibility and actuality of a judgment) with the traditional, non-modal understanding (...) of it (in terms of the giving and withholding of assent). I conclude by suggesting that Kant prefers the former because he conceives of knowledge on Aristotle’s model: as a progress in the mind from capacity to act. (shrink)

This chapter aims to contribute to the endeavour of investigating nonhuman animals as experiencing subjects in their own right with their own species-specific histories. Our focus is on the examination of pain experience in animals. We argue that there is need for more research in which pain experience in animals is accounted for in species-specific terms. Making use of empirical studies in the fields of neurobiology, evolutionary-developmental biology, comparative psychology, and cognitive ethology, we try to offer a phenomenological analysis of (...) indications and expressions of pain experience in animals. We attempt to show how different animals are capable of indicating and expressing specific and unique experiences of pain in terms of their particular species, evolution, and places of living in human and natural contexts. (shrink)

In five works spanning a decade, Philip E. Tetlock's interest in counterfactuals has changed. He began with an optimistic desire to make social science more rigorous by identifying best practices in the absence of non-imagined controls for experimentation. Soon, however, he adopted a more pessimistic analysis of the cognitive and psychological barriers facing experts. This shift was brought on by an awareness that experts are not rational Bayesians who continually update their theories to keep up with new information; but instead (...) are affected by political, cognitive, and psychological heuristics, including hindsight bias, cognitive conservatism, and the fundamental attribution error. But techniques of computational simulation-involving the rigorous production of large numbers of counterfactual worlds-make it possible to mitigate both problems that Tetlock identifies: that history, produced only once, is a lousy teacher; and that humans, with their collection of non-Bayesian heuristics, are lousy pupils. Tetlock was wrong to reject this approach as theoretically promising but rhetorically and practically impractical. (shrink)

Do Morals Matter? is an accessible and informed guide to contemporary ethical issues that reflects upon the intersection of religion and morality. An informal yet informed guide through the key ethical issues we are facing today, from moral decision making in business and medicine, to the uncertainty of war and terrorism, and the condition of our environment. Reflects on religion’s intersection with morality, exploring the challenge of pluralism in major world religions, and the question of Humanism and God’s role in (...) ethics. Considers the forecast of future situations that will be affected by today’s ethical decisions. Questions what accounts for the variances in ethical beliefs in different cultures, and how we properly reassess our conceptions of ethical standards as new issues arise. Written by the internationally regarded Ian Markham, Dean of Hartford Seminary and author of numerous books on world religions and ethics. (shrink)

Health services internationally struggle to ensure health care is “person-centered” (or similar). In part, this is because there are many interpretations of “person-centered care” (and near synonyms), some of which seem unrealistic for some patients or situations and obscure the intrinsic value of patients’ experiences of health care delivery. The general concern behind calls for person-centered care is an ethical one: Patients should be “treated as persons.” We made novel use of insights from the capabilities approach to characterize person-centered care (...) as care that recognizes and cultivates the capabilities associated with the concept of persons. This characterization unifies key features from previous characterisations and can render person-centered care applicable to diverse patients and situations. By tying person-centered care to intrinsically valuable capability outcomes, it incorporates a requirement for responsiveness to individuals and explains why person-centered care is required independently of any contribution it may make to health gain. (shrink)

In five works spanning a decade, Philip E. Tetlock's interest in counterfactuals has changed. He began with an optimistic desire to make social science more rigorous by identifying best practices in the absence of non-imagined controls for experimentation. Soon, however, he adopted a more pessimistic analysis of the cognitive and psychological barriers facing experts. This shift was brought on by an awareness that experts are not rational Bayesians who continually update their theories to keep up with new information; but instead (...) are affected by political, cognitive, and psychological heuristics, including hindsight bias, cognitive conservatism, and the fundamental attribution error. But techniques of computational simulation-involving the rigorous production of large numbers of counterfactual worlds-make it possible to mitigate both problems that Tetlock identifies: that history, produced only once, is a lousy teacher; and that humans, with their collection of non-Bayesian heuristics, are lousy pupils. Tetlock was wrong to reject this approach as theoretically promising but rhetorically and practically impractical. (shrink)

Yet many in the USA and Europe are not familiar with his important work; this book seeks to rectify that gap.In Globalization, Ethics and Islam, Jewish, ...

This article re-evaluates the significance attributed to Hecataeus¿ encounter with the Theban priests described by Herodotus (2.143) by setting it against the evidence of Late Period Egyptian representations of the past. In the first part a critique is offered of various approaches Classicists have taken to this episode and its impact on Greek historiography. Classicists have generally imagined this as an encounter in which the young, dynamic and creative Greeks construct an image of the static, ossified and incredibly old culture (...) of the Egyptians, a move which reveals deeper assumptions in the scholarly discourse on Greeks and ¿other¿ cultures in the Mediterranean world. But the civilization that Herodotus confronted in his long excursus on Egypt was not an abstract, eternal Egypt. Rather, it was the Egypt of his own day, at a specific historical moment ¿ a culture with a particular understanding of its own long history. The second part presents evidence of lengthy Late Period priestly genealogies, and more general archaizing tendencies. Remarkable examples survive of the sort of visual genealogy which would have impressed upon the travelling Greek historians the long continuum of the Egyptian past. These include statues with genealogical inscriptions and relief sculptures representing generations of priests succeeding to their fathers¿ office. These priestly evocations of a present firmly anchored in the Egyptian past are part of a wider pattern of cultivating links with the historical past in the Late Period of Egyptian history. Thus, it is not simply the marvel of a massive expanse of time which Herodotus encountered in Egypt, but a mediated cultural awareness of that time. The third part of the essay argues that Herodotus used this long human past presented by the Egyptian priests in order to criticize genealogical and mythical representations of the past and develop the notion of an historical past. On the basis of this example, the article concludes by urging a reconsideration of the scholarly paradigm for imagining the encounter between Greeks and ¿others¿ in ethnographic discourse in order to recognize the agency of the Egyptian priests, and other non-Greek ¿informants¿. (shrink)

The value scenario is a useful tool in the sheaf of methods within value sensitive design. When envisioning new technology, this tool supports the designer in speculatively considering relevant stakeholders, values expressed or rebuffed by an artifact’s design, and tensions that may exist between those values. This paper explores how science fiction stories can serve as value scenarios to supplement traditional historical methods, especially when informants are no longer accessible.

Health services internationally struggle to ensure health care is “person-centered” (or similar). In part, this is because there are many interpretations of “person-centered care” (and near synonyms), some of which seem unrealistic for some patients or situations and obscure the intrinsic value of patients’ experiences of health care delivery. The general concern behind calls for person-centered care is an ethical one: Patients should be “treated as persons.” We made novel use of insights from the capabilities approach to characterize person-centered care (...) as care that recognizes and cultivates the capabilities associated with the concept of persons. This characterization unifies key features from previous characterisations and can render person-centered care applicable to diverse patients and situations. By tying person-centered care to intrinsically valuable capability outcomes, it incorporates a requirement for responsiveness to individuals and explains why person-centered care is required independently of any contribution it may make to health gain. (shrink)

Everyday Writing in the Graeco-Roman East. By Roger S. Bagnall. Sather Classical Lectures, vol. 69. Berkeley and Los Angeles: University of California Press, 2011. Pp. xiv + 179, illus. $49.95.

The nature of moral action versus moral judgment has been extensively debated in numerous disciplines. We introduce Virtual Reality (VR) moral paradigms examining the action individuals take in a high emotionally arousing, direct action-focused, moral scenario. In two studies involving qualitatively different populations, we found a greater endorsement of utilitarian responses–killing one in order to save many others–when action was required in moral virtual dilemmas compared to their judgment counterparts. Heart rate in virtual moral dilemmas was significantly increased when compared (...) to both judgment counterparts and control virtual tasks. Our research suggests that moral action may be viewed as an independent construct to moral judgment, with VR methods delivering new prospects for investigating and assessing moral behaviour. (shrink)

Recent advances in virtual technologies have allowed the investigation of simulated moral actions in aversive moral dilemmas. Previous studies have employed diverse populations in order to explore these actions, with little research considering the significance of occupation on moral decision-making. For the first time, in this study we have investigated simulated moral actions in Virtual Reality made by professionally trained paramedics and fire service incident commanders who are frequently faced with and must respond to moral dilemmas. We found that specially (...) trained individuals showed distinct empathic and related personality trait scores and that these declined with years of experience working in the profession. Supporting the theory that these professionals develop resilience in moral conflict, reduced emotional arousal was observed during virtual simulations of a distressing dilemma. Furthermore, trained professionals demonstrated less regret following the execution of a moral action in virtual reality when compared to untrained control populations. We showed that, contrary to previous research, trained individuals made the same moral judgments and moral actions as untrained individuals, though showing less arousal and regret. In the face of increasing concerns regarding empathy decline in healthcare professionals, we suggest that the nature of this decline is complex and likely reflects the development of a necessary emotional resilience to distressing events. (shrink)

Several recent findings support the notion that changes in the environment can be implicitly represented by the visual system. S. R. Mitroff, D. J. Simons, and S. L. Franconeri (2002) challenged this view and proposed alternative interpretations based on explicit strategies. Across 4 experiments, the current study finds no empirical support for such alternative proposals. Experiment 1 shows that subjects do not rely on unchanged items when locating an unaware change. Experiments 2 and 3 show that unaware changes affect performance (...) even when they occur at an unpredictable location. Experiment 4 shows that the unaware congruency effect does not depend simply on the pattern of the final display. The authors point to converging evidence from other methodologies and highlight several weaknesses in Mitroff et al.’s theoretical arguments. It is concluded here that implicit representation of change provides the most parsimonious explanation for both past and present findings. (shrink)

This chapter examines the ancient Stoic theory of the physical composition of pneuma, how its composition relates to pneuma’s many causal roles in Stoic philosophy, and to what extent each of the first three leaders of the Stoic school accepted the claim that pneuma pervades the cosmos. I argue that pneuma is a compound of fire and air. Furthermore, many functions of pneuma can be reduced to the functions of these elements. Finally, it is likely that each of the early (...) Stoics posited a pervasive cosmic pneuma. This paper also explores the nature of pneuma’s tensile movement and offers an account of fire and air’s roles in causing its motion. (shrink)

We have far less evidence for Aristotle’s reception of Protagoras than we like to think, and the evidence we do have is somewhere we hardly ever look. With one exception, every reference Aristotle makes to the Measure Doctrine—Protagoras’ claim that humans are the ‘measure of all things —concerns the Doctrine as amplified in Plato’s Theaetetus, and the ‘Protagoras’ in question is Plato’s fictional character as fictional. Metaph. I 1, 1053a35–b3 provides the only exception, where Aristotle offers an anomalous reading of (...) the Doctrine incompatible with the others. The chapter interprets I 1, 1053a35–b3 and concludes that Aristotle attributes the anomalous reading to Protagoras himself. The chapter argues further that every other reference to the Doctrine derives from the Theaetetus. Aristotle formulates ‘the theory of Protagoras’ according to Plato’s self-refutation argument, and his argument that it denies the Principle of Non-contradiction includes premisses from Plato’s argument that are out of place in Aristotle’s own. He moreover attributes to ‘Protagoras’ arguments and dialectical demands that the fictional Protagoras makes in his so-called ‘apology’, so his target is specifically a Platonic invention and not the historical person. This leaves only Metaph. I 1 1053a35–b3 to join his six other references to the historical Protagoras, which makes it Aristotle’s only engagement with the Measure Doctrine as the actual view of his predecessor. (shrink)

_Hans Kelsen and the Natural Law Tradition_ provides the first sustained examination of Hans Kelsen’s critical engagement, itself founded upon a distinctive theory of legal positivism, with the Natural Law Tradition.

This paper seeks to develop a Wittgensteinian response to the Scope Problem, which ensnares a theory of truth considered as inflationary. The scope problem challenges any inflationary truth theory to provide a single explanation which can account for the concept of truth given the diversity of statements that most of us are willing to accept as true. In line with Wittgenstein's later-views on language and philosophy and their corresponding functions, this paper provides a general diagnosis of the problem: similarities in (...) syntax do not entail similarities in meaning. By employing Wittgenstein's metaphors (i.e., "handles" and "tools") and an analysis via concrete cases and analogies, this paper responds to the challenge presented by the Scope Problem, not by providing a satisfactory definition of truth but rather by providing its "dissolution" á la Wittgenstein. (shrink)

"The four essays in this volume constitute Derrida's most explicit and sustained reflection on the art work as pictorial artifact, a reflection partly by way of philosophical aesthetics, partly by way of a commentary on art works and art scholarship. The illustrations are excellent, and the translators, who clearly see their work as both a rendering and a transformation, add yet another dimension to this richly layered composition. Indispensable to collections emphasizing art criticism and aesthetics."—Alexander Gelley, _Library Journal_.

This paper puts together an ancientand a recent approach to classificatory language, thought, and ontology.It includes on the one hand an interpretation of Aristotle's ten categories,with remarks on his first category, called (or translated as) substancein the Categories or What a thing is in the Topics. On the other hand is the ideaof domain-specific cognitive abilities urged in contemporary developmentalpsychology. Each family of ideas can be used to understand the other. Neitherthe metaphysical nor the psychological approach is intrinsically morefundamental; they (...) complement each other. The paper incidentally clarifies distinct uses of the word category in different disciplines, and also attempts to make explicit several notions of domain. It also examines Aristotle's most exotic and least discussed categories, being-in-a-position (e.g., sitting) and having-(on) (e.g., armour). Finally the paper suggests a tentative connectionbetween Fred Sommers' theory of types and Aristotle's first category. (shrink)

This paper puts together an ancientand a recent approach to classificatory language, thought, and ontology.It includes on the one hand an interpretation of Aristotle's ten categories,with remarks on his first category, called (or translated as) substancein the Categories or What a thing is in the Topics. On the other hand is the ideaof domain-specific cognitive abilities urged in contemporary developmentalpsychology. Each family of ideas can be used to understand the other. Neitherthe metaphysical nor the psychological approach is intrinsically morefundamental; they (...) complement each other. The paper incidentally clarifies distinct uses of the word “category” in different disciplines, and also attempts to make explicit several notions of “domain”. It also examines Aristotle's most exotic and least discussed categories, being-in-a-position (e.g., sitting) and having-(on) (e.g., armour). Finally the paper suggests a tentative connectionbetween Fred Sommers' theory of types and Aristotle's first category. (shrink)

The four volumes of Neil Ker's Medieval Manuscripts in British Libraries were published by Oxford University Press between 1969 and 1992. They comprise a catalogue of about 3,000 manuscripts in Latin and Western European vernaculars in hitherto uncatalogued or inadequately catalogued institutional collections in the United Kingdom and form a major research tool for humanist scholars. The index volume, produced under the direction of A. G. Watson, a former pupil of Ker's and now his literary executor, and I. C. Cunningham, (...) formerly Keeper of Manuscripts in the National Library of Scotland, provides a variety of indexes, including authors/titles; owners; geographical origins and dates of manuscripts; vernacular manuscripts; Latin and vernacular incipits; manuscripts cited; repertories cited; and iconography. There are also lists of recent accessions to libraries and of manuscripts that have migrated from one institution to another. (shrink)

Teachers are brain changers. Thus it would seem obvious that an understanding of the brain – the organ of learning – would be critical to a teacher’s readiness to work with students. Unfortunately, in traditional public, public-charter, private, parochial, and home schools across the country, most teachers lack an understanding of how the brain receives, filters, consolidates, and applies learning for both the short and long term. Neuroteach was therefore written to help solve the problem teachers and school leaders have (...) in knowing how to bring the growing body of educational neuroscience research into the design of their schools, classrooms, and work with each individual student. It is our hope, that Neuroteach will help ensure that one day, every student –regardless of zip code or school type—will learn and develop with the guidance of a teacher who knows the research behind how his or her brain works and learns. (shrink)

A region-based model of physical space is one in which the primitive spatial entities are regions, rather than points, and in which the primitive spatial relations take regions, rather than points, as their relata. Historically, the most intensively investigated region-based models are those whose primitive relations are topological in character; and the study of the topology of physical space from a region-based perspective has come to be called mereotopology. This paper concentrates on a mereotopological formalism originally introduced by Whitehead, which (...) employs a single primitive binary relation C(x, y) (read: "x is in contact with y"). Thus, in this formalism, all topological facts supervene on facts about contact. Because of its potential application to theories of qualitative spatial reasoning, Whitehead's primitive has recently been the subject of scrutiny from within the Artificial Intelligence community. Various results regarding the mereotopology of the Euclidean plane have been obtained, settling such issues as expressive power, axiomatization and the existence of alternative models. The contribution of the present paper is to extend some of these results to the mereotopology of three-dimensional Euclidean space. Specifically, we show that, in a first-order setting where variables range over tame subsets of ℝ³, Whitehead's primitive is maximally expressive for topological relations; and we deduce a corollary constraining the possible region-based models of the space we inhabit. (shrink)

The first study of its kind, The Impact of Idealism assesses the impact of classical German philosophy on science, religion and culture. This third volume explores German Idealism's impact on the literature, art and aesthetics of the last two centuries. Each essay focuses on the legacy of an idea or concept from the high point of German philosophy around 1800, tracing out its influence on the intervening period and its importance for contemporary discussions. As well as a broad geographical and (...) historical range, including Greek tragedy, George Eliot, Thomas Mann and Samuel Beckett, and key musicians and artists such as Wagner, Andy Warhol and Frank Lloyd Wright, the volume's thematic focus is broad. Engaging closely with the key aesthetic texts of German Idealism, this collection uses examples from literature, music, art, architecture and museum studies to demonstrate Idealism's continuing influence. (shrink)

In the same intellectual league as Grotius, Hobbes and Locke, but today less well known, Samuel Pufendorf was an early modern master of political, juridical, historical and theological thought. Trained in an erudite humanism, he brought his copious command of ancient and modern literature to bear on precisely honed arguments designed to engage directly with contemporary political and religious problems. Through his fundamental reconstruction of the discipline of natural law, Pufendorf offered a new rationale for the sovereign territorial state, providing (...) it with non-religious foundations in order to fit it for governance of multi-religious societies and to protect his own Protestant faith. He also drew on his humanist learning to write important political histories, a significant lay theology, and vivid polemics against his many opponents. This volume makes the full scope of his thought and writing accessible to English readers for the first time"--publisher's website. (shrink)

A formal and idealised understanding of intentionality as a mental process is a central topic within the classical Husserlian phenomenological analysis of consciousness. This paper does not define Husserl’s stance, because that has been achieved elsewhere (Kern, 1977, 1986, 1988; Kern & Marbach, 2001; Marbach, 1988, 1993, 2005; Owen, 2006; Zahavi, 2003). This paper shows how intentionality informs therapy theory and practice. Husserl’s ideas are taken to the psychotherapy relationship in order to explain what it means for consciousness to have (...) intentionality in various ways. The role of intentionality in psychopathology and its treatment within cognitive behavioural therapy is explained as a way of showing how understanding intentionality creates a medum for the delivery of care. Indo-Pacific Journal of Phenomenology , Volume 7, Edition 1 May 2007. (shrink)

Martin Heidegger wrote one and only one preface for a scholarly work on his thinking, and it was for William J. Richardson’s study Heidegger: Through Phenomenology to Thought, first published in 1963. Ever since, both Heidegger’s Preface and Richardson’s groundbreaking book have played an important role in Heidegger scholarship. Much has been discussed about these texts over the decades, but what has not been available to students and scholars up to this point is Richardson’s original comments and questions to Heidegger (...) that led to the famous Preface. These are published here for the first time both in the German original and in our English translation. In our commentary we 1) discuss how Heidegger’s Preface came about, 2) explain the source and status of the materials published here, and 3) pair selected passages from Richardson’s text with Heidegger’s reply in his Preface to highlight the consonance of their thinking. (shrink)

Libertarianism has often found itself under attack from those with misplaced maternal instincts, who champion the state as the honorable protector of the vulnerable – and there is no one more in need of protection than a helpless infant. Consequently, much of the vitriol aimed at libertarianism and its laissez-faire attitude has included morbid references to child abuse and exploitation which would supposedly result from its implementation. It is therefore imperative that more work be done on the topic of children’s (...) rights in order to reinforce the philosophical framework developed by Murray Rothbard [9] and expanded on by Walter Block and others [2], [3], [5], [6]. The purpose of this paper is to provide an independent rational foundation for the conclusions drawn by Block and co-authors [2], [5] and to expand on parts that are insufficient. (shrink)

Bayesians take “definite” or “single-case” probabilities to be basic. Definite probabilities attach to closed formulas or propositions. We write them here using small caps: PROB(P) and PROB(P/Q). Most objective probability theories begin instead with “indefinite” or “general” probabilities (sometimes called “statistical probabilities”). Indefinite probabilities attach to open formulas or propositions. We write indefinite probabilities using lower case “prob” and free variables: prob(Bx/Ax). The indefinite probability of an A being a B is not about any particular A, but rather about the (...) property of being an A. In this respect, its logical form is the same as that of relative frequencies. For instance, we might talk about the probability of a human baby being female. That probability is about human babies in general — not about individuals. If we examine a baby and determine conclusively that she is female, then the definite probability of her being female is 1, but that does not alter the indefinite probability of human babies in general being female. Most objective approaches to probability tie probabilities to relative frequencies in some way, and the resulting probabilities have the same logical form as the relative frequencies. That is, they are indefinite probabilities. The simplest theories identify indefinite probabilities with relative frequencies.3 It is often objected that such “finite frequency theories” are inadequate because our probability judgments often diverge from relative frequencies. For example, we can talk about a coin being fair (and so the indefinite probability of a flip landing heads is 0.5) even when it is flipped only once and then destroyed (in which case the relative frequency is either 1 or 0). For understanding such indefinite probabilities, it has been suggested that we need a notion of probability that talks about possible instances of properties as well as actual instances.. (shrink)

Political representation lies at the core of modern politics. Democracies, with their vast numbers of citizens, could not operate without representative institutions. Yet relations between the democratic ideal and the everyday practice of political representation have never been well defined and remain the subject of vigorous debate among historians, political theorists, lawyers, and citizens. In this volume, an eminent group of scholars move forward the debates about political representation on a number of fronts. Drawing on insights from political science, history, (...) political theory, economics, and anthropology, the authors provide much-needed clarity to some of the most vexing questions about political representation. They also reveal new and enlightening perspectives on this fundamental political practice. Topics discussed include representation before democracy, political parties, minorities, electoral competition, and ideology. This volume is essential reading for anyone interested in the ideal and the reality of political representation. (shrink)

Machine learning algorithms may radically improve our ability to diagnose and treat disease. For moral, legal, and scientific reasons, it is essential that doctors and patients be able to understand and explain the predictions of these models. Scalable, customisable, and ethical solutions can be achieved by working together with relevant stakeholders, including patients, data scientists, and policy makers.